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The Mad Scientist Who’s Beating Aging
Your body does not fail all at once. Aging starts when cells quietly shift into survival mode and never come back out. In this episode, you go inside the thinking of a true medical outlier to understand how stress, travel, toxins, and metabolic overload reprogram cells, shut down energy, and accelerate aging, and how restoring mitochondrial function can reverse that trajectory from the inside out.
Host Dave Asprey sits down with Dr. Theodore Achacoso and Boomer Anderson, leaders in Health Optimization Medicine and Practice. Dr. Achacoso is a physician-scientist and the founding pioneer of Health Optimization Medicine, known for his work on cellular networks, metabolomics, and mitochondrial function. Boomer Anderson is the CEO of Smarter Not Harder and Troscriptions, where he focuses on translating complex biology into practical tools for human performance and longevity.
Together, they unpack how cells respond to perceived threats through the Cell Danger Response, why mitochondria control energy, inflammation, and repair, and why chasing disease labels misses the real drivers of aging. The discussion covers methylene blue as an electron recycler, why LDL cholesterol plays a role in detoxification and immune signaling, how fasting and ketosis shift metabolism between repair and growth, and why sleep optimization, circadian rhythm, and light exposure matter even more when you travel. They also explore neuroplasticity, consciousness, nootropics, supplements, and why health optimization works best when you restore balance instead of forcing outcomes.
You’ll Learn:
• What the Cell Danger Response is and how it reshapes aging and performance
• How mitochondria sense stress before symptoms appear
• Why cellular energy controls resilience, sleep, and longevity
• How methylene blue supports mitochondrial electron flow
• Why fasting and ketosis shift metabolism between repair and growth
• How travel, light, and circadian disruption affect aging
• Why very low LDL can impair detoxification and immune signaling
• How supplements and nootropics fit into a Smarter Not Harder strategy
• Why real anti-aging starts at the cellular level, not with disease labels
Thank you to our sponsors!
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Timestamps:
0:00 – Trailer
1:25 – Introduction & Guest Background
3:11 – Health Optimization Medicine Origins
4:26 – Root Causes of Health vs Disease
8:19 – Medicinal Plants & Nootropics
11:25 – Travel & Jet Lag Solutions
13:42 – Cell Danger Response
18:57 – LDL & Lipopolysaccharides
20:42 – Cellular Model & First Principles
22:55 – Consciousness & Mitochondria
25:46 – Nanotechnology Research
27:44 – Open Source & Autonomy
31:17 – Blue Cannatine Development
34:48 – Methylene Blue Products
36:22 – Metformin Discussion
38:00 – Dosing & Cordycepin
41:25 – Closing & Discount Code
Resources:
• Get A Discount On All Troscription Products with code ‘dave’ at: https://troscriptions.com/
• Learn More About Methylene Blue From My Full Masterclass Covering The Topic: https://daveasprey.com/mb/
• Discover More About The ‘Health Optimization Medicine and Practice’ From Our Guests: https://homehope.org/
• Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/
• Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/
Website: https://daveasprey.com
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The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave’s favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Collective: https://www.ourupgradecollective.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
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Graduation isn’t the finish line… It’s the launch. 🎓🚀
We asked our graduates what’s coming next – from big summer plans to taking the first steps into their careers. Wherever they’re headed, we couldn’t be prouder.
What’s your next move? Job, travel, masters, or something unexpected? Drop it in the comments 💬
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Consumers are in search of belonging in an increasingly fragmented world.
Learn more about collective belonging here: https://www.diageo.com/en/news-and-media/consumer-trends-report/foresight-report-2025/collective-belonging
Diageo’s distilled report exposes a new consumer behaviour trend emerging to better interconnect diverse communities in the offline and online world. With the development of niche tech communities, online celebrity fandoms and growing voices in diversity, consumers are finding one another through their shared passions, creating save environments to express themselves.
About Diageo:
With over 200 brands sold in more than 180 countries, our portfolio offers something for every taste and celebration. We are a global leader in beverage alcohol with an outstanding collection of brands across spirits and beer; including Guinness, Johnnie Walker and Baileys. We aim for the highest standards in all that we do, mixing responsibility and reliability with incredible flair. Celebrating life, every day, everywhere.
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Watch more about our Distilled report: https://www.youtube.com/playlist?list=PL7yKiyUVNV3eL7QdIaxUy81MGD2-qCbLs
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Diageo – Celebrating life, Every day, Everywhere.
#WeAreDiageo #Diageo #DiageoDistilled
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For more great videos, check out our YouTube Channel:
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LinkedIn: https://www.linkedin.com/company/diageo/
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【Creative Statement / Artistic & Safety Disclosure】 Viewing is strictly prohibited for those under 18 years of age.
1. Nature of Content: This channel primarily features original short films and television series, falling under the “Artistic” category in YouTube’s EDSA policy.
2. Child Safety: The minor characters featured in this episode are all professional/voluntary actors. All filming was conducted under the real-time supervision of a guardian to ensure a safe and compliant environment. Please do not imitate this behavior.
3. Production Goal: The videos explore themes such as life philosophy, family, and workplace through fictional narratives and do not involve any dangerous, suggestive, or inappropriate behavior.
⚠️ VIEWER DISCRETION ADVISEDThis video features a fictional drama series involving mature themes (relationships, family conflict). It is intended for a general audience (13+) and is NOT made for kids.All characters depicted are portrayed by actors.
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This is 【Hawaii Drama】, providing you with the latest, hottest and best short plays on time every day!
Thank you for your attention and likes！🥰🥰🥰
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All content on this channel consists of original licensed mini-dramas with official authorization. The works are fictional portrayals for entertainment purposes only. Viewer discretion is advised as some content may be unsuitable for minors under applicable regulations.
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మరిన్ని Health Updates కోసం మా ఛానల్ ను సబ్స్క్రయిబ్ చేసుకోండి.
https://www.youtube.com/channel/UCDe0kQ21BcjkHPuPqworDxw
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చిటికెలో గ్యాస్ ప్రాబ్లెమ్ తగ్గించే బెస్ట్ టిప్https://youtu.be/aZwwhPB71HM
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ఈ గింజల రసంతో ఎంతటి షుగర్ అయినా దిగొస్తుంది https://youtu.be/Hh2GfGczS_Y
డ్రై ఫ్రూట్స్ ని ఇలా తింటేనే ఆరోగ్యం https://youtu.be/m2VINLXPTj8
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నిమిషాల్లో మలం జర్రున జారిపడేలా సింపుల్ టెక్నిక్ https://youtu.be/W0im8Td9p0g
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మరిన్ని Health Updates కోసం మా ఛానల్ ను సబ్స్క్రయిబ్ చేసుకోండి.
📝హైదరాబాద్ పరిసరాల్లో చిలుకూరి బాలాజీ టెంపుల్ సమీపంలో అహ్లాదకరమైన వాతావరణంలో సంజీవిని నేచుర్ క్యూర్ ఆశ్రమం ఉంది.
ప్రకృతి సిద్ధమైన వాతావరణంలో ప్రకృతి వైద్య చికిత్స చేస్తున్న హైదరాబాద్ నగరపు ఏకైక ఆసుపత్రి సంజీవిని నేచుర్ క్యూర్ ఆశ్రమం.
ఆశ్రమ నిర్వాహకులు డా.మధుబాబు ప్రకృతి వైద్యం (BNYS)లో డబుల్ గోల్డ్ మెడలిస్ట్. అలాగే ఆల్టర్నేటివ్ మెడిసిన్ లో MD కోర్సు పూర్తి చేశారు. ఆక్యుపంక్చర్ చికిత్సా విధానంలో పీజీ డిప్లొమా చేశారు. ప్రాణిక్ హీలింగ్ కోర్సు సైతం చదివారు.
డా.మధుబాబు గారి నుంచి మీరు ఎటువంటి సమస్యకైనా ఉచితంగా సలహాలు పొందవచ్చు.
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