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This Brain Trick Feels Like Cheating (Do THIS)

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Most brain decline, mood instability, and impulsive behavior start with a breakdown in how the brain’s immune cells produce and use energy. This episode shows how mitochondrial health inside microglia influences cognition, emotion, and long-term brain resilience, and how everyday inputs quietly push those systems toward damage or repair.

Host Dave Asprey is joined by Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work focuses on the intersection of neurology, nutrition, metabolism, and brain health. A Fellow of the American College of Nutrition and member of the Editorial Board of the Journal of Alzheimer’s Disease, Dr. Perlmutter brings decades of clinical and research experience to this conversation on how inflammation and mitochondrial function shape the brain across the lifespan.

Together, they explore how microglial cells shift their behavior based on metabolic conditions, and how those shifts influence neurodegeneration, emotional regulation, impulse control, and cognitive performance. The discussion covers real-world inputs that shape these systems, including sleep optimization, fasting, ketosis, glucose regulation, gut signaling, environmental toxins, and tools referenced in the episode such as red and infrared light, 40 Hz light and sound, hyperbaric oxygen, lithium, nicotine, supplements, nootropics, GLP-1 agonists, and dietary approaches like carnivore and ketosis. The conversation connects brain biology to lived experience, showing how metabolism influences behavior, decision making, and long-term human performance through a Smarter Not Harder lens.

You’ll Learn:
• How microglia shift between supportive and destructive states and why metabolism drives that change
• How mitochondrial function inside immune cells influences inflammation and brain resilience
• How inflammation affects the prefrontal cortex, impulse control, and reward-driven behavior
• What the episode says about GLP-1 agonists and behavior changes like reduced cravings and gambling
• How gut-derived signaling and short-chain fatty acid balance (butyrate vs propionate) relates to brain function
• How tools like red and infrared light, hyperbaric oxygen, and 40 Hz light and sound connect to microglia
• The lifestyle levers discussed in the episode: sleep optimization, fasting, ketosis, glucose control, and toxin reduction
• The compounds mentioned, including lithium, nicotine, urolithin A, CoQ10, rosmarinic acid, and dihydromyricetin

Thank you to our sponsors!

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Timestamps:
0:00 – Introduction
1:45 – Autism Spectrum
4:38 – Alzheimer’s & Beta Amyloid
7:02 – Brain Immune Cells
8:06 – GLP-1 & Parkinson’s
10:44 – M1 vs M2 Microglia
13:08 – Pharmaceutical Microdosing
15:51 – Gene Therapy
19:09 – Mold & Toxins
21:58 – Environmental Pollution
26:05 – MPTP Discovery
29:07 – Healing Interventions
31:39 – Light & Sound Therapy
36:35 – Mitochondrial Function
44:57 – Inflammation & Prefrontal Cortex
48:00 – GLP-1 Global Impact
52:11 – Mitochondrial Community
56:05 – Consciousness & The Field
1:00:00 – Psychedelics
1:06:35 – Death & Knowing
1:09:06 – Heart-Brain Connection
1:11:06 – Closing Thoughts

Resources:
• Learn More About Dr. Perlmutter at: https://drperlmutter.com/
• Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/
• Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/
• Dave Asprey’s Latest News | Go to https://daveasprey.com/ to join Inside Track today.

Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr

The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/

Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave’s favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Collective: https://www.ourupgradecollective.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com

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Fashion UK

M-Trends Report 2026 Yayınlandı. Siber Saldırılar Artık Daha Hızlı, Daha Sessiz ve Daha Yıkıcı..

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Siber güvenlikte yeni durum, “saldırıyı önleyebilir miyiz?” değil; “saldırı gerçekleştiğinde ayakta kalabilir miyiz?” 🚨

📊 Siber güvenlik dünyasında en çok referans alınan yıllık yayınlarından biri olan M-Trends 2026 Raporu yayımlandı. Google Tehdit İstihbarat Grubu (GTIG) ve Mandiant’ın 2025 yılında yürüttüğü 500.000 saati aşkın olay incelemesine dayanan bu rapor, tehdit ortamının artık tamamen yeni bir evreye geçtiğini açıkça gösteriyor.

⚡ Saldırılar artık daha hızlı gelişiyor, sistemlerde daha uzun süre fark edilmeden kalabiliyor ve etkileri çok daha yıkıcı olabiliyor. Ancak asıl dikkat çekici nokta şu: Saldırganlar yapay zekâ ve zero-day açıkları gibi gelişmiş yöntemlerden giderek daha fazla yararlansa da, başarılı sızmaların büyük bölümü hâlâ insan hataları, süreç eksiklikleri ve zayıf sistem kontrollerinden kaynaklanıyor.

🧩 Bu da bize çok net bir gerçeği gösteriyor: Siber güvenlik yalnızca teknoloji meselesi değil. İnsan, süreç ve kontrol mekanizmaları yeterince güçlü değilse, en gelişmiş güvenlik çözümleri bile tek başına yeterli olmuyor.

Üstelik tehditlerin hızı da ciddi biçimde artmış durumda. Raporda, ilk erişim ile saldırının ikinci aşamaya devredilmesi arasındaki sürenin 2022’de 8 saatin üzerindeyken 2025’te 22 saniyeye kadar düştüğü vurgulanıyor. Saldırganların meşru araçları kullanarak izlerini gizlemesi de bu tabloyu daha kritik hâle getiriyor. Yani güvenlik ekiplerinin müdahale etme süresi her zamankinden daha dar.⏱️

💡 Bu nedenle artık yalnızca saldırıları engellemeye odaklanan bir yaklaşım yeterli değil. Erken tespit, hızlı müdahale ve operasyonel dayanıklılık yeni dönemin temel öncelikleri arasında. Çünkü bugün siber güvenlik, yalnızca IT ekiplerinin konusu değil; kurumların iş sürekliliğini ve dayanıklılığını doğrudan etkileyen stratejik bir alan.

Bu yeni gerçeklikte fark yaratan şey, sahip olunan teknoloji kadar, o teknolojiyi doğru yöneten insan kaynağı ve güçlü süreçlerdir.

Siz de OAK Academy eğitimleriyle uzmanlığınızı bir üst seviyeye taşıyın, siber dayanıklılığın mimarı olun.🛡️

🔗 Rapora erişim: https://cloud.google.com/security/resources/m-trends

🔔 Daha fazla siber güvenlik içeriği için bizi takipte kalın!

#SiberGüvenlik #CyberSecurity #MTrends2026 #Mandiant #GoogleCloud #BilgiGüvenliği #FidyeYazılımı #Phishing #Exploit #Ransomware #ITSecurity #Hacker #SOC #BlueTeam #RedTeam #GRC #SiberDayanıklılık #OAKAcademy #Teknoloji #DijitalDönüşüm #DwellTime #Handoff #Google

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“Hide in the Fitting Room,” the Bridal Shop Owner Warned Me Before the Wedding

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Before the wedding, the bridal shop owner leaned in and whispered, “Hide in the fitting room.” Why did she warn me, and what was happening that made her urge me to hide? The title leaves the danger—and what I discovered—unrevealed.

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Front page app me mobile number change kaise kare | how to change mobile number in front page app

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About :- maine aapko bataya hai ki Front page app me mobile number change kaise kare | how to change mobile number in front …

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InfoQ Software Architecture and Design Trends Report – April 2024.

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InfoQ Software Architecture and Design Trends Report – April 2024

https://bit.ly/4aJpEkf

#CybersecurityAlerts
#SoftwareSecurity
#PatchManagement
#ITSecurityNews
#DataProtectionUpdates
#TechSecurity
#CompanyPatches
#IndustrySecurity
#CyberThreatAlert
#InnovationSecurity

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Fashion UK

【FULL】I Waited 5 Years to Marry Him—Then Caught Him Secretly Voting Against Our Wedding

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📻 Show Title:Trading a Liar for a Billionaire King

For five years, florist Vivian has waited to marry wealthy heir Arthur Winston, believing his family’s annual rejection of their marriage is the only thing keeping them apart. But when she catches Arthur secretly casting the deciding vote against their wedding, she discovers he has been deliberately delaying their future to keep his beautiful assistant Olivia by his side. Heartbroken by years of lies and manipulation, Vivian finally walks away and accepts a marriage proposal from Adrian, a powerful man who has secretly loved her since she saved his life seven years ago. As Arthur realizes what he’s lost and Olivia’s schemes grow increasingly dangerous, Vivian must decide whether to look back at her first love or embrace the man who has always chosen her.
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😎 All content on this channel is officially licensed 📚

✅ All series on this channel are artistic expressions, in compliance with EDSA requirements. The scenes included are for cinematic effect, and some materials have been harmlessly processed. Please do not attempt to imitate!
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