A breakthrough drug for ovarian cancer that is kinder on the body and extends lives is now available on the NHS.

The drug, called mirvetuximab soravtansine, is a known as a “biological missile” as it delivers chemotherapy drugs direct to the cancerous tissue rather than to the whole body – reducing debilitating side-effects.

Up to 400 patients a year in England could benefit from the new treatment – the first for hard-to-treat ovarian cancer in 20 years.
There are nearly 7,750 cases of ovarian cancer in the UK each year.

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At least 11 Palestinians have been killed, including women and children, and dozens wounded in Israeli air strikes across Gaza City, according to medical sources and eyewitnesses.

Israeli aircraft struck at least four residential buildings in the Sheikh Radwan and Tel al-Hawa neighbourhoods and Shati refugee camp in the early hours of Thursday, causing powerful explosions and panic among residents.

Among videos posted on social media, said to be the aftermath of the attacks, were distressing images of people trying to leave a building engulfed in fire in Shati camp.

There was no immediate comment from the Israeli military.

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The first televised debate from the Makerfield by-election has taken place in a special edition of Question Time.

Adam and Chris reunite after Question Time to discuss all the biggest moments, including Andy Burnham’s clearest confirmation yet that he will stand in a Labour leadership election – but will he trigger one?

00:00 Intro
00:32 Trust in politicians and why this by-election is happening
01:32 Andy Burnham confirms he would enter a Labour leadership contest
07:03 Audience anger at Keir Starmer and Reform’s response
09:12 Robert Kenyon challenged over historic social media posts
12:32 Policing and the debate over recent disorder
17:04 Housing, the EU and local issues on the campaign trail
19:30 Outro

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Chris tells Adam what it was like meeting Robert Kenyon, the Reform UK candidate in the Makerfield by-election and how he and …

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