Today, after speaking to Rachel Reeves in what’s likely to be her final interview as chancellor, Laura speaks to Paddy about what we might get from the new administration.

Andy Burnham has talked about “room within [the Labour] manifesto for movement on tax.”

What does that mean in practice?

We’ve got some clues from Labour insiders.

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A rare genetic condition that causes people to grow much shorter than average could help scientists understand how to prevent cancer and diabetes.

About 840 people worldwide have Laron syndrome, a rare condition that prevents the body producing the growth hormone IGF-1 – and many of those live in a small region in Ecuador.

Researchers studying this community have found that people with Laron syndrome appear to have much lower rates of cancer and diabetes, raising questions about whether their genetics could help develop future treatments.

Scientists hope understanding the condition could unlock new ways to tackle age-related diseases.

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Keir Starmer has given his final address as UK prime minister, calling the job “the privilege of [his] life.” Delivering his final address …

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The US launched a wave of strikes against Iran for the sixth night in a row, its military said, as the two sides battled over control of …

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The US said it had launched a fresh wave of strikes against Iran on Wednesday as President Donald Trump warned Tehran it “better behave”.

The US military said “Iranian military capabilities used to threaten vessels” moving through the Strait of Hormuz had been targeted. Air defences also sounded in the capital Tehran, according to state media.
Iran meanwhile said it had struck US military targets in the region, including in Bahrain and Kuwait, as a fifth day of renewed hostilities strained their preliminary deal to end the war.

Iran’s top negotiator, Mohammad Bagher Ghalibaf, told state media Tehran had “no reason” to abide by the deal if it did not benefit from it.
Trump had threatened late on Tuesday to attack bridges and power plants should Iran not return to talks next week.

Asked by reporters late on Wednesday whether he would give a deadline before doing so, he responded: “I ‌don’t like giving ​deadlines, but they pretty ⁠much know, they know ​the story… ​they ​better ​behave.”

He later told delegates at a defence summit that Iran was “not happy right now”.

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