Iran and the United States have carried out on the biggest exchange of attacks since July, stoking fears of a return to all out war.

Iran said 18 people were killed and more than 100 injured in latest US bombardment. It accused the US of committing a war crime by striking a wedding in the city of Kuhestak, killing four people including two children. The Pentagon responded by saying it does not target civilians.

In retaliation, Iran launched a wave of strikes against American targets in the region, including in Kuwait, Jordan, Iraq and Bahrain.

President Trump is warning that the US is prepared to carry out further strikes in response to those attacks.

There are warnings of a serious impact on the global economy, with further disruption to oil and gas supplies, affecting inflation and global borrowing costs.

Clive Myrie presents BBC News at Ten reporting by Caroline Hawley and Jeremy Bowen.

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In Nepal, a huge wave of mud and debris has left hundreds dead and rescuers racing to find survivors in treacherous conditions.

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There are fears of more flash floods in Nepal, as rescuers scramble through villages engulfed in rock and mud in a desperate search for survivors of the flash floods that have left at least 1,400 missing and hundreds dead. It is feared that the final death toll may be much higher.

Survivors have been giving harrowing accounts of how their entire families were wiped away in the catastrophe.

Hundreds of foreign nationals are desperately waiting to hear from loved ones thought to be caught in the disaster. Nepalese authorities say at least 380 people are confirmed to have died.

The region is popular with trekkers from around the world and is a pilgrimage site for Hindus and Buddhists, visited by tens of thousands of pilgrims each year.

Travellers from at least 28 countries, are among those missing following the catastrophe. The Nepalese authorities says among those missing are citizens of India, China, Malaysia, the Philippines, South Korea, Singapore, Kazakhstan, Japan, the US, Canada, Australia, New Zealand, the UK, Germany, Belgium, Finland, ​France, Hungary, Italy, the Netherlands, Ireland, Portugal, Serbia, Spain, Sweden, Russia, Belarus, Lithuania, Latvia, South Africa and Israel.

Tens of thousands of tourists make their way through Nepal annually. The disaster struck at the time of the year when people, especially Indian tourists, visit the area.

State media in China, which controls Tibet, reported three dead and at least 558 missing there. Among these are 260 foreign nationals. It is not clear if these figures overlap with the numbers provided by Nepal.

It appears that collapse of mountain glaciers triggered the disaster and there are fears of an imminent risk of further flash flooding without warning. Climate change is known to be driving faster glacier melt in the Hindu Kush Himalaya region, but scientists say it is too soon to pinpoint its role in this specific event.

Jane Hill presents BBC News at Ten reporting by Azadeh Moshiri, Laura Bicker and Justin Rowlatt.

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More than 600 people have died following Wednesday’s devastating flash flood in Nepal.

At least 2,426 people are missing, Nepal’s disaster management authority says, as rescue operations continue for a fourth day.

Families of the missing – including at least 517 foreign nationals – are waiting for news on the whereabouts of their loved ones.

Emergency teams are warning that rain is making it difficult to reach some of the worst-affected areas.

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The gunman behind the shooting in an Orlando gay nightclub first became known to the FBI in 2013, according to officials. Fifty people are now known to have died after Omar Mateen opened fire.

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