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First ‘personalised’ melanoma skin cancer vaccine trial under way in UK | BBC News

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A trial of the world’s first “personalised” vaccine against the deadliest form of skin cancer is under way in the UK.

The mRNA vaccine is designed to help patient’s immune systems to recognise and wipe out cancerous melanoma cells.

It is personalised to the individual patient – with its make-up created to match the unique genetic signature of the patient’s own tumour, and works by instructing the body to make proteins or antibodies that attack markers or antigens found only on those cancer cells.

Experts in some other countries, including Australia, are also trying it on patients, to gather more evidence and see whether it should be rolled out more widely.

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The 30-year cold case of Tupac Shakur | BBC News

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The drive-by shooting that killed rap superstar Tupac Shakur on 7 September 1996 changed the trajectory of hip-hop and elevated the rapper from the face of the genre to a cultural icon.

His killing became one of popular culture’s great mysteries, with countless theories but no arrests until 2023, when Duane “Keffe D” Davis was unexpectedly charged with murdering the famous rapper.

Davis, a 63-year-old former gang boss, is due to stand trial in Las Vegas.

Fame Under Fire host, Anoushka Mutanda-Dougherty, speaks to Shaun Kent, resident trial attorney, about the case.

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#Tupac #TupacTrial #KeffeD #FameUnderFire #BBCNews

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Cancer patients were given a PERSONALISED vaccine – and it’s working | BBC News

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A new personalised vaccine given in combination with an immunotherapy drug has stopped skin cancer returning in patients during a trial.

This could be a major moment in cancer treatment. But how did it work – and what could it mean for future patients?

In this video…

01:11 What is melanoma and who took part in this trial?
02:01 Trial results
03:26 Personalised vaccines
04:21 How are personalised vaccines made?
05:00 Production challenges of personalised vaccines
05:57 Moderna and Merck share surge
06:29 When could patients get this vaccine?

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What happened to Harry and Meghan’s American dream? #UKRoyals #BBCNews

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What are the main risks and side effects of vaping? #Vaping #Health #BBCNews

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Mega Brothel: Inside one of Europe’s largest legal borthels – BBC News

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Newsnight’s Jim Reed was shown around Paradise Stuttgart, one of Europe’s largest legal brothels.

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